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Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
Antibodies that bind ... leading to an allergic ... Sensitization" to Allergen ... Initial exposure to allergen ... complexes bind
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... causes development ... of allergen-specific ... Allergic reaction ... Initial exposure to allergen
Angioedema - Classification Diagnosis and Treatment Types of Angioedema: • Acute allergic angioedema - Usually occurs with
Angioedema: • Acute allergic ... exposure • Non-allergic ... cell-mediated in > 90% of cases ... or avoiding the allergen ... Treatment #management #allergy
Eosinophils (Eos) and hypereosinophilia (HE) Caused by eosinophilopoietic cytokines Common causes: - Drug reaction - Helminth infection -
hypereosinophilia (HE) Caused ... cytokines Common causes ... infection - Allergic ... disease Rare causes ... + T cells) - Allergic
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
of lgE Abs that bind ... leading to an allergic ... cell surfaces causes ... leading to an allergic ... causes development
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... lgE antibodies bind ... When the specific allergen ... Pathophysiology #Allergy
NAACP mnemonic for the major causes of Eosinophilia N = Neoplasia (CML, Hodgkins lymphoma) A =
for the major causes ... lymphoma) A = Allergy ... #Differential #Causes
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... lgM antibodies bind ... reactions #types #allergy
Causes of Facial Weakness - Differential Diagnosis Algorithm Forehead Sparing = Central cause - Most commonly
Causes of Facial ... Sparing = Central cause ... Diagnosis #Algorithm #Causes ... #neurology #sparing
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy • Central or peripheral neurologic disease
Causes of Proximal ... or peripheral neurologic ... #differential #causes ... #neurology
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