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diagnosis hematology management differential reactions classification table algorithm comparison eosinophilia hypersensitivity product syndrome types anemia anesthesia anesthesiology aplastic basophilia basophils
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
NEJM 1999 - ICU FOCUS ... blood is a liquid ... Blood saves lives ... unnecessary and cause ... #Thresholds #Hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... - Allergic ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... • Allergic reaction ... Causes purpura & ... TRALI): Leading cause ... diagnosis #management #hematology
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
lgE antibodies bind ... When the specific allergen ... - Red blood cell ... destruction after transfusion ... with mismatched blood
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... • Acne • Allergy ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
TRALI vs TACO - Transfusion ... plasma volume transfusion ... of high parity blood ... without other cause ... #Reactions #hematology
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... lgM antibodies bind ... Examples: Acute transfusion ... reactions #types #allergy
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
maintained fever CAUSES ... urological device • Blood ... transfusion • ... Allergic reaction ... • Intracranial blood
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... for secondary causes ... eosinophilia (common causes ... are asthma, allergy ... Differential #diagnosis #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
the total white blood ... released during an allergic ... Chickenpox Other Causes ... Differential #Diagnosis #causes ... #hematology #basophils
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