169 results
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
of lgE Abs that bind ... cell surfaces causes ... causes development ... An allergic reaction ... #Allergic #Reactions
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... lgM antibodies bind ... #types #allergy
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Antibodies that bind ... leading to an allergic ... reaction. ... Sensitization" to Allergen ... complexes bind
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Penicillin-induced drug reaction ... Dermatitis (ie. reaction ... #Allergic #Reactions
Allergic Reaction Classification
Type 1 reaction: Acute anaphylactic reaction
Type 2 reaction: Cytotoxic reaction
Type 3 reaction: Immune complex
Type
Allergic Reaction ... Type 2 reaction ... Type 3 reaction ... #Allergic #Reaction ... Classification #Types #allergy
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... causes development ... of allergen-specific ... Allergic reaction ... Initial exposure to allergen
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
cytokines Common causes ... : - Drug reaction ... infection - Allergic ... reaction - Atopic ... + T cells) - Allergic
Drug Treatment of Anaphylaxis and Allergic Reactions
First-Line Therapy 
 - Epinephrine 
 - Oxygen 
 -
Anaphylaxis and Allergic ... Reactions First-Line ... #Medications #Allergy
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema: • Acute allergic ... exposure • Non-allergic ... drug reaction - ... cell-mediated in > 90% of cases ... or avoiding the allergen
Cross-Reactivity of Penicillins and Cephalosporins

Cross reactivity of penicillin-allergic patients to cephalosporins has more to do with
of penicillin-allergic ... Cephalosporins #Allergy ... Management #Carbapenem #Reaction