101 results
Allergic Contact Dermatitis 
- Erythematous, indurated, scaly plaques 
- T-cell mediated, delayed-type hypersensitivity response to exogenous
Allergic Contact ... Contact #Dermatitis #Allergic ... #Allergy #Dermatology ... #Rash #Skin
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Antibodies that bind ... leading to an allergic ... reaction. ... Sensitization" to Allergen ... complexes bind
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
of lgE Abs that bind ... cell surfaces causes ... causes development ... An allergic reaction ... #Allergic #Reactions
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... causes development ... of allergen-specific ... Allergic reaction ... Initial exposure to allergen
Types of hypersensitivity reactions

Type I - lgE-Mediated, Within I Hour (Anaphylaxis)
Type II - IgG or IgM
hypersensitivity reactions ... Days to Weeks (Rash ... hypersensitivity #reactions ... Classification #Allergy
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
cytokines Common causes ... : - Drug reaction ... infection - Allergic ... reaction - Atopic ... + T cells) - Allergic
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy
Mild Reaction - Itching, Minor rash
Mild Reaction ... Itching, Minor rash ... Maculopapular rash ... urticaria OR Unknown reaction ... nephritis, Drug rash
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... lgM antibodies bind ... #types #allergy
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... • Nonmalignant hematologic ... syndrome, POEMS • Reaction ... post-splenectomy, Exercise, Allergic ... reactions Matthew
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Vesiculobullous Skin Rash ... Bullous impetigo - Reaction ... diabeticorum) - Reaction ... Vesiculobullous #SkinRash #dermatology ... Diagnosis #Algorithm #causes