49 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... lgE antibodies bind ... When the specific allergen ... destruction after transfusion ... #Diagnosis #Reactions
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... Penicillin-induced drug reaction ... Dermatitis (ie. reaction ... #Allergic #Reactions ... Classification #Diagnosis
Allergic Reaction Classification
Type 1 reaction: Acute anaphylactic reaction
Type 2 reaction: Cytotoxic reaction
Type 3 reaction: Immune complex
Type
Allergic Reaction ... Type 2 reaction ... #Allergic #Reaction ... Classification #Types #allergy ... #diagnosis
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Antibodies that bind ... leading to an allergic ... reaction. ... Sensitization" to Allergen ... complexes bind
Estimated Incidence of Transfusion Reactions
Graphical Depiction of transfusion reactions ordered from most highest to lowest incidence.
#Diagnosis
Reactions Graphical ... Depiction of transfusion ... reactions ordered ... #Diagnosis #Blood ... #Reactions #Events
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
of lgE Abs that bind ... reaction • Type ... An allergic reaction ... #Allergic #Reactions ... Classification #Diagnosis
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Reaction (FNHTR ... Reaction (AHTR) ... Reaction (DHTR) ... - Allergic ... #diagnosis #management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Reactions Immune ... Reaction (FNHTR ... Reaction (AHTR) ... • Allergic reaction ... #diagnosis #management
Algorithm for the Evaluation and Management of Transfusion Reactions

This algorithm was developed by Dr. Eric Madden,
Management of Transfusion ... Reactions This ... #Transfusion #Reactions ... #Algorithm #Diagnosis
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... Mechanism of Action: Allergen-specific ... lgM antibodies bind ... Examples: Acute transfusion ... #types #allergy