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Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... Clinical Features ... #Syndrome #diagnosis ... #management #treatment
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Demyelinating Disease ... Poliomyelitis, Guillain-Barre ... heavy metals), Critical ... #differential #diagnosis
Campylobacter
Clinical 
 • Fever 
 • Abdominal pain 
 • Diarrhea (bloody stools) 
 • Vomiting
Campylobacter Clinical ... • Guillain-Barré ... syndrome Management ... Antibiotics for severe disease ... Campylobacter #Diagnosis
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... and Differential Diagnosis ... 109 mm Hg) with clinical ... Renal parenchymal disease ... , and Guillain-Barre
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days)
Exclude:
1. Causes of acute diarrhea
2. Lactose intolerance
3.
Causes of acute ... Systemic disease ... Chronic #Diarrhea #management ... #algorithm #workup ... #diagnosis #differential
COPD phenotypes:  Blue Bloaters vs. Pink Puffers
The two most stereotypical forms of COPD are pink
physiology and clinical ... have an overlap syndrome ... obesity-hypoventilation syndrome ... airflow obstruction causes ... #Diagnosis #COPD
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... the underlying pathophysiology ... #Syndrome #diagnosis ... #management #neurology
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
structural heart disease ... carotid sinus syndrome ... further guide management ... should be guided by clinical ... the underlying disease
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... DDX - Other causes ... infections (Epstein-Barr ... syndrome, HIV) ... #management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... maintained fever CAUSES ... #Differential #Causes ... Anesthesia #Checklist #Diagnosis ... #Management #Workup