7 results
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Hypomagnesemia - ... losses - Chronic diarrhea ... Familial renal Mg wasting ... #Differential # ... Low #Magnesium #Table
IBS-D Pharmacotherapy

Loperamide
Rifaximin
Eluxadoline
Alosetron
Antispasmodics
Tricyclic antidepressants
SSRIs

#IBSD #IBS #Diarrhea #Irritable #Bowel #Syndrome #pharmacology #table #comparison #management #treatment
#IBSD #IBS #Diarrhea ... Irritable #Bowel #Syndrome ... #pharmacology # ... table #comparison
Hypokalemia - Differential Diagnosis
Poor Intake 
 - Starvation
 - Anorexia
GI Losses 
 - Vomiting / NG
Hypokalemia - Differential ... NG drainage - Diarrhea ... type 4) - Salt wasting ... - Polyuria - Hypomagnesemia ... Low #Potassium #Table
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Causes of Hypomagnesemia ... biliary fistula - Diarrhea ... aldosteronism #Hypomagnesemia ... Causes #diagnosis #differential ... medications #drugs #pharmacology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Side Effects: Hypomagnesemia ... constipation, diarrhea ... constipation, diarrhea ... #medications #pharmacology ... #table #comparison
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Alcoholism (worsened by hypomagnesemia ... ), Eating disorders ... nasogastric suction, Diarrhea ... Fever Other: - Hypomagnesemia ... Hypokalemia #Causes #differential
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
hypokalemia, mild hypomagnesemia ... renal potassium wasting ... ) • Hypomagnesemia ... ratio 0.5%) Differential ... Congenital chloride diarrhea