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diagnosis differential hematology leukemia naildisorders nephrology oncology abg acid acidbase base bloodgas cll common cvid fatigue gas hypogammaglobulinemia hypokalemia immunecompromised
Primary Dermatologic Nail Disorders - Differential Diagnosis Algorithm Nail Plate - Pitting • Psoriasis • Alopecia Areata Nail
Primary Dermatologic ... Nail Disorders ... Paronychia • Chronic ... Telangiectasia • SLE ... #causes
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Splenomegaly - CTD (SLE ... Kasabach-Merritt syndrome ... Associated - SLE ... mountain spotted fever ... #nonpalpable #dermatology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Arthritis • SLE ... • Somatization Disorder ... Fatigue Syndrome ... #causes
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Abnormality • SLE ... discoloration) • Chronic ... • Nephrotic syndrome ... #causes
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
Acid Base Disorders ... D-lactate (short bowel syndrome ... acidosis: - Diarrhea ... Anxiety, pain, fever ... #AcidBase #disorders
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... Headaches, bone pain, fever ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Lymphadenopathy • HSM • Fevers
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... Autoimmunity • Chronic ... • Infectious diarrhea ... DDX - Other causes ... : • Nephrotic syndrome
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Causes of Fever ... Bronchitis • Chronic ... Diarrhea • Giardia ... Infection #Fever ... #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... non-Hodgkin lymphoma SLL ... Lymphadenopathy • Fevers ... lymphoproliferative disorders ... • Richter’s Syndrome
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... hypomagnesemia), Eating disorders ... nasogastric suction, Diarrhea ... - Diuretics (carbonic ... , Heat stroke, Fever
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