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management coagulation abnormal dermatomyositis hodgkins lymphoma manifestations prolonged pt rheumatology skin algorithm antimda5 antimda5dm antinxp2 antinxp2dm bleeding bruising classification comparison
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... the PT and the aPTT ... • Reduced liver ... #diagnosis #differential ... #hematology #coagulation
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... : INR/PT, aPTT(liver ... #Diagnosis #Causes ... #Workup #hematology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... Calmettes #Cutaneous ... myelodysplastic #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... #diagnosis #differential ... #hematology #coagulation
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... Vasculitis #dermpath #dermatology ... signs #lesions #diagnosis ... #clinical #manifestations ... pathology #lesions #differential
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... DIC • Severe Liver ... INR < 2.3 - APTT ... #Coagulation #diagnosis ... #management #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS) - Differential ... nemaline myopathy Cutaneous-centered ... #Diagnosis #hematology ... #oncology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Diagnosis Portal ... >10 mmHg - clinically ... hepatorenal syndrome Clues ... #Diagnosis #causes ... #hepatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
the spleen or liver ... disease: GI, neuro, cutaneous ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
discoloration) • Liver ... Systemic #Secondary #dermatology ... #Differential # ... Diagnosis #Algorithm ... #causes
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