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differential coagulation pt abnormal disorders management ptt treatment algorithm arterial bleeding bruising dic disseminated embolism evaluation hemophilia hemostasis hypertension inr
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
K Antagonists, Heparin ... to identify the cause ... of Prolonged APTT ... #prolonged #diagnosis ... #hematology #evaluation
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... PTT • Prolonged ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology #coagulation
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Early liver disease ... Reduced liver synthesis ... #Prolonged #Causes ... #diagnosis #differential ... #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... (e.g. heparin contamination ... • Reduced liver ... #Prolonged #Causes ... #hematology #coagulation
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin
Thromboplastin Time (PTT ... inhibitor • Liver ... elevated in: • Heparin ... Thromboplastin #laboratory #hematology ... #diagnosis
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... hepatorenal syndrome Clues ... sarcoidosis) • Liver ... #Differential #Diagnosis ... #causes #hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thrombocytopenia • Prolonged ... DIC • Severe Liver ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... : INR/PT, aPTT(liver ... bypass), LFT (liver ... #Differential #Diagnosis ... #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... is prolonged, but ... mixing study (aPTT ... normal in mild cases ... Management #treatment #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... deficiency • Liver ... #Differential #Diagnosis ... #hematology #rheumatology ... #nonpalpable #dermatology
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