6 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Tests - Differential ... Diagnosis Algorithm ... or AST > ALP): ... Cholestatic Pattern (ALP ... LFTs #Elevated #Abnormal
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... Diagnosis Algorithm ... • Pregnancy - AFLP ... disease US — Normal ... #Diagnosis #Algorithm
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
/ULN ALT) / (Alk ... phos/ULN ALP) ... - If both are normal ... • Near normal ... chemistry #diagnosis #differential
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... Findings: • ↑AST/ALT ... (5-10x ULN), ↑Tbili ... infiltration) Differential ... iMedEducation #AFLP
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
& AST normal or ... • Bilirubin - Normal ... obstruction • ALP ... > 1.5 x ULN • ... bile ducts Differential
Primary Biliary Cirrhosis - Management
A. Initiate therapy 
 - Initiate 1st line therapy with UDCA (13-15
Biliary Cirrhosis - Management ... line therapy if ALP ... > 1.5x ULN and/ ... or abnormal conjugated ... Non-pharmacological management