11 results
diagnosis hepatology lfts treatment algorithm biliary cirrhosis elevated neurology sclerosis transaminitis workup aih als amyotrophic ascites autoimmune calcium causes chemistry
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
combination of UMN ... (3) primary lateral ... involvement • UMN ... conditions listed in differential ... neurology #diagnosis #management
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Severe - ALT >15X ULN ... Mild - ALT < 5x ULN ... Ducts - PBC
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... Severe ALT > 15x ULN ... disease US — Normal ... Bile Ducts • PSC ... #LiverEnzymes #Differential
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... • ALT & AST normal ... • ALP > 1.5 x ULN ... bile ducts Differential ... malignancy #Primary
Hypercalcemia Evaluation 1) Clinical clues - Is the patient symptomatic? - Family history? - Have you done
→ Primary hyperapara ... likely - Mid range/ULN ... → Primary hyperpara ... • If all normal ... Hypercalcemia #workup #differential
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
reported (eg AIH-PBC ... upper limit of normal ... Hepatitis (eg Viral) Management ... AND IgG > 2x ULN ... AIH #Diagnosis #Management
Ascites - Diagnosis and Management Summary Paracentesis studies: cell count + differential, albumin, protein, culture • Serum-ascites-albumin-gradient
Diagnosis and Management ... : cell count + differential ... source • SBP: PMN ... count (WBC x PMN ... Ascites #Diagnosis #Management
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
R-value: Serum (ALT/ULN ... ALT) / (Alk phos/ULN ... - If both are normal ... of ALP • Near normal ... chemistry #diagnosis #differential
Primary Biliary Cirrhosis - Management A. Initiate therapy - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... if ALP > 1.5x ULN ... and/or abnormal ... survey disease #PBC ... #Primary #Biliary
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN ... Hyperreflexia, Clonus, Babinski ... Progressive MS • Primary ... sclerosis #diagnosis #management
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