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hepatology diagnosis algorithm biliary cirrhosis lfts autoimmune causes cholangitis elevated hepatitis liverenzymes liverfunctiontests transaminitis treatment workup
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Severe - ALT >15X ULN ... Viral, Ischemia, AIH ... Ducts - PBC
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... • Drugs • AIH ... disease US — Normal ... Bile Ducts • PSC ... #LiverEnzymes #Differential
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
been reported (eg AIH-PBC ... upper limit of normal ... If suspected, AIH ... Hepatitis (eg Viral) Management ... #Diagnosis #Management
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... • ALT & AST normal ... • ALP > 1.5 x ULN ... bile ducts Differential ... malignancy #Primary
Primary Biliary Cirrhosis - Management A. Initiate therapy - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... if ALP > 1.5x ULN ... and/or abnormal ... survey disease #PBC ... #Primary #Biliary
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