7 results
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... involving both UMN ... combination of UMN ... conditions listed in differential ... neurology #diagnosis #management
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Severe - ALT >15X ULN ... Mild - ALT < 5x ULN ... - CBD stone, Biliary
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... Severe ALT > 15x ULN ... disease US — Normal ... Duct Stone • Biliary ... #LiverEnzymes #Differential
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... No extrahepatic biliary ... • ALP > 1.5 x ULN ... bile ducts Differential
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... AST/ALT (5-10x ULN ... infiltration) Differential ... obgyn #diagnosis #management ... #pathophysiology
Acute Pancreatitis - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Epigastric abdominal pain (90%, characteristically
Diagnosis and Management ... 2) Lipase > 3x ULN ... • Imaging: US (biliary ... diagnosis, can be normal ... MRCP (necrosis, biliary
Primary Biliary Cirrhosis - Management
A. Initiate therapy 
 - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... Cirrhosis - Management ... if ALP > 1.5x ULN ... and/or abnormal ... #PBC #Primary #Biliary