13 results
diagnosis hepatology lfts algorithm biliary cirrhosis liver pbc primary transaminitis treatment aflp aih als amyotrophic apml ascites autoimmune bandemia causes
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... involving both UMN ... combination of UMN ... conditions listed in differential ... neurology #diagnosis #management
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Severe - ALT >15X ULN ... Mild - ALT < 5x ULN ... Algorithm #diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... Severe ALT > 15x ULN ... disease US — Normal ... Others #LFTs #Hepatology ... #LiverEnzymes #Differential
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... AST/ALT (5-10x ULN ... infiltration) Differential ... Liver #Pregnancy #hepatology ... #pathophysiology
Ascites - Diagnosis and Management Summary Paracentesis studies: cell count + differential, albumin, protein, culture • Serum-ascites-albumin-gradient
Diagnosis and Management ... : cell count + differential ... count (WBC x PMN ... Ascites #Diagnosis #Management ... #Summary #Hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
upper limit of normal ... Hepatitis (eg Viral) Management ... AND IgG > 2x ULN ... AIH #Diagnosis #Management ... #Hepatology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
) Differential ... • Abnormal temperature ... bacteremia • Abnormal ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... • ALT & AST normal ... • ALP > 1.5 x ULN ... bile ducts Differential ... diagnosis #workup #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
R-value: Serum (ALT/ULN ... ALT) / (Alk phos/ULN ... - If both are normal ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
(>10^6 IU/mL), normal ... (<2000 IU/mL), normal ... IU/mL and ALT > ULN ... #Indications #management ... #hepatology
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