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diagnosis hepatology biliary cirrhosis neurology pbc sclerosis treatment workup aflp als amyotrophic calcium cholangitis elevated endocrinology evaluation fatty hypercalcemia lateral
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... combination of UMN ... (3) primary lateral ... conditions listed in differential ... neurology #diagnosis #management
Hypercalcemia Evaluation 1) Clinical clues - Is the patient symptomatic? - Family history? - Have you done
→ Primary hyperapara ... likely - Mid range/ULN ... → Primary hyperpara ... • If all normal ... Hypercalcemia #workup #differential
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... • ALP > 1.5 x ULN ... bile ducts Differential ... malignancy #Primary
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... AST/ALT (5-10x ULN ... infiltration) Differential ... obgyn #diagnosis #management ... #pathophysiology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN ... Hyperreflexia, Clonus, Babinski ... Progressive MS • Primary ... sclerosis #diagnosis #management
Primary Biliary Cirrhosis - Management A. Initiate therapy - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... Cirrhosis - Management ... if ALP > 1.5x ULN ... and/or abnormal ... disease #PBC #Primary
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