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hepatology diagnosis lfts algorithm pbc primary transaminitis causes chemistry cholangitis elevated interpretation liver liverenzymes liverfunctiontests management rvalue treatment workup
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Severe - ALT >15X ULN ... Congenital, Others, Cirrhosis ... - CBD stone, Biliary
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... disease US — Normal ... Infiltrative • Cirrhosis ... Duct Stone • Biliary ... #LiverEnzymes #Differential
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Cirrhosis (PBC) ... • ALP > 1.5 x ULN ... bile ducts Differential ... #Cirrhosis #PBC
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
R-value: Serum (ALT/ULN ... ALT) / (Alk phos/ULN ... - If both are normal ... hepatitis: < 1 • Cirrhosis ... chemistry #diagnosis #differential
Primary Biliary Cirrhosis - Management A. Initiate therapy - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... Cirrhosis - Management ... if ALP > 1.5x ULN ... and/or abnormal ... #PBC #Primary #Biliary
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