15 results
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
combination of UMN ... involvement • UMN ... conditions listed in differential ... diagnosis column Treatment ... neurology #diagnosis #management
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Severe - ALT >15X ULN ... LFTs #Elevated #Abnormal ... Algorithm #diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... Severe ALT > 15x ULN ... disease US — Normal ... Others #LFTs #Hepatology ... #LiverEnzymes #Differential
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
upper limit of normal ... Hepatitis (eg Viral) Management ... regarding need for treatment ... AIH #Diagnosis #Management ... #Hepatology
Ascites - Diagnosis and Management Summary
Paracentesis studies: cell count + differential, albumin, protein, culture
 • Serum-ascites-albumin-gradient
Diagnosis and Management ... : cell count + differential ... count (WBC x PMN ... Ascites #Diagnosis #Management ... #Summary #Hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
(>10^6 IU/mL), normal ... (<2000 IU/mL), normal ... IU/mL and ALT > ULN ... #Indications #management ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
AST/ALT (5-10x ULN ... infiltration) Differential ... Intrahepatic Cholestasis Management ... Liver #Pregnancy #hepatology ... obgyn #diagnosis #management
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
R-value: Serum (ALT/ULN ... ALT) / (Alk phos/ULN ... - If both are normal ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN ... Hyperreflexia, Clonus, Babinski ... Multiple Sclerosis Treatment ... sclerosis #diagnosis #management ... #neurology #treatment
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
• ALT & AST normal ... • Bilirubin - Normal ... • ALP > 1.5 x ULN ... bile ducts Differential ... diagnosis #workup #hepatology