11 results
diagnosis hepatology treatment differential lfts algorithm biliary cirrhosis pbc primary workup acute aih autoimmune calcium cardiology causes chemistry cholangitis endocrinology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Algorithm for Transaminitis ... Severe - ALT >15X ULN ... kwburak #LFTs #Elevated ... #Abnormal #Transaminitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Severe ALT > 15x ULN ... Moderate ALT 5-15x ULN ... Mild ALT < 5x ULN ... disease US — Normal
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
IgG typically elevated ... upper limit of normal ... Hepatitis (eg Viral) Management ... AND IgG > 2x ULN ... AIH #Diagnosis #Management
Hypercalcemia Evaluation 1) Clinical clues - Is the patient symptomatic? - Family history? - Have you done
likely - Mid range/ULN ... FeCa <1 %) - Low normal ... • If all normal ... endocrinology #calcium #elevated
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
R-value: Serum (ALT/ULN ... ALT) / (Alk phos/ULN ... specificity to elevated ... - If both are normal ... differential #Hepatology #transaminitis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
• ALT & AST normal ... or slightly elevated ... • Bilirubin - Normal ... early on but elevated ... • ALP > 1.5 x ULN
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN ... Hyperreflexia, Clonus, Babinski ... sclerosis #diagnosis #management
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
(>10^6 IU/mL), normal ... (<2000 IU/mL), normal ... (>10^6 IU/mL), normal ... IU/mL and ALT > ULN ... #Indications #management
Acute Pancreatitis - Diagnosis and Management - GrepMed Handbook Presentation: • Epigastric abdominal pain (90%, characteristically
Diagnosis and Management ... 2) Lipase > 3x ULN ... diagnosis, can be normal ... hemorrhage Management ... diagnosis and management
Heart failure with Reduced Ejection Fraction (HFrEF) Clinical Presentation 1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Specific Signs: elevated ... compensatory upregulation un ... heartfailure #diagnosis #management
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