7 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Differential Diagnosis Algorithm ... kwburak #LFTs #Elevated ... #Algorithm #diagnosis ... #hepatology #LiverFunctionTests
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... disease US — Normal ... Others #LFTs #Hepatology ... Differential #Diagnosis #Algorithm
Ascites - Differential Diagnosis and Workup Algorithm

•
Perform paracentesis:
 • Cell count and diff 
 • Total
Diagnosis and Workup ... Algorithm • ... ascites WBC and PMN ... Differential #Diagnosis #Algorithm ... gastroenterology #hepatology
Hypercalcemia Evaluation
1) Clinical clues
 - Is the patient symptomatic?
 - Family history?
 - Have you done
likely - Mid range/ULN ... • If all normal ... Hypercalcemia #workup ... endocrinology #calcium #elevated ... #evaluation #workup
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
IgG typically elevated ... upper limit of normal ... ALT + AST > 5x ULN ... AND IgG > 2x ULN ... Diagnosis #Management #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
or slightly elevated ... early on but elevated ... • ALP > 1.5 x ULN ... cholangitis #diagnosis #workup ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
R-value: Serum (ALT/ULN ... ALT) / (Alk phos/ULN ... specificity to elevated ... - If both are normal ... #differential #Hepatology