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diagnosis hepatology management algorithm differential transaminitis aih autoimmune biliary causes chemistry cirrhosis elevated gastroenterology hbv hepatitis hepatitisb hepbv icucard indications
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Severe - ALT >15X ULN ... Moderate - ALT 5-15X ULN ... Mild - ALT < 5x ULN ... Burak @kwburak #LFTs
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Severe ALT > 15x ULN ... Moderate ALT 5-15x ULN ... Mild ALT < 5x ULN ... disease US — Normal ... • Others #LFTs
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... R-value: Serum (ALT/ULN ... ALT) / (Alk phos/ULN ... - If both are normal ... transaminitis #LFTs
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
subclinical disease to acute ... upper limit of normal ... ALT + AST > 5x ULN ... AND IgG > 2x ULN ... regarding need for treatment
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
(>10^6 IU/mL), normal ... (<2000 IU/mL), normal ... IU/mL and ALT > ULN ... immunosuppression • Acute ... > 3 mg/dL) or acute
Acute Pancreatitis - Diagnosis and Management - GrepMed Handbook Presentation: • Epigastric abdominal pain (90%, characteristically
Acute Pancreatitis ... 2) Lipase > 3x ULN ... Lipase, Ca2+, LFTs ... #Pancreatitis #Acute ... Diagnosis #Management #Treatment
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN ... Hyperreflexia, Clonus, Babinski ... Multiple Sclerosis Treatment ... symptoms) • Acute ... management #neurology #treatment
#ICUCard RENAL GFR 90-131 mL/min ((140-age)*Wt)/(72*Cr) Glomerular Filtration Rate (Cockcroft) CI Cr 90-131 mL/min (CrU * volume)/CrS Creatinine Clearance FENa 0.0-1.0 % ((U/P Na)/(U/P Cr))*100 Fractional Excretion of Na+ Na req mEq (125-Na)*0.6*Wt Required Sodium FE Urea
Urea 20-70 % ((UUN ... ТРСО2 → Тнсоз acute ... IPCO2 → ІнСО3 acute ... g/6.25 - (24h UUN ... PaCO2 > 50mmHg (acute
Primary Biliary Cirrhosis - Management A. Initiate therapy - Initiate 1st line therapy with UDCA (13-15
if ALP > 1.5x ULN ... and/or abnormal ... Cirrhosis #Management #Treatment
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