3 results
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
dorsum of the hands ... red papules -> Gottron ... -> Heliotrope Rash ... #PM #Diagnosis ... Pathophysiology #Signs
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... papules • Inverse Gottron ... • Mechanic's hands ... #dermatology #diagnosis
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
rash (Gottron papules ... and Gottron sign ... are elevated < PM ... and DM • CPK 10X ... • Mechanic's hands