12 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... Microangiopathic hemolytic ... cell disease Bite ... #Analysis #hematology ... #microscopy #interpretation
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
polychromatophilic cells ... arrow) Peripheral smear ... #anemia #Hematology ... #Pathology #Smear ... #Microscopy
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Peripheral Smear ... blood loss, Acute hemolysis ... , deficiency anemia ... Vasculitides, IBD, Celiac disease ... syndrome, POEMS • Reaction
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... AIHA, Transfusion reactions ... Defects: Sickle cell anemia ... Peripheral Blood Smear ... Differential #Diagnosis #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
flank pain, dark urine ... Graft Versus Host Disease ... potassium from lysed cells ... Borrellia (Lyme disease ... diagnosis #management #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
flank pain, dark urine ... Blood products contain ... potassium from lysed cells ... of transfused products ... diagnosis #management #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
IgM) • Blood smear ... sensitize red blood cells ... passage of red-brown urine ... #hemolytic #anemia ... #hematology #diagnosis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... Fibrin degradation products ... Peripheral blood smear ... anemia Indirect ... Diagnosis #Workup #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... Myeloproliferative Disease ... abnormal under a microscope ... Peripheral blood smear ... Syndromes #diagnosis #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
• Peripheral smear ... lymphocytes, smudge cells ... 5) Symptoms of anemia ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology