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diagnosis hematology leukemia management clinical anemia chronic cll derm differential lymphocytic aplastic arm blood causes clark hemeonc honc mds melanoma
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
peripheral-blood smear ... revealed 25% plasma cells ... PlasmaCell #Leukemia #Smear ... #NEJM
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
peripheral-blood smear ... acanthocytes (or spur cells ... Spur cells acquire ... #NEJM #clinical ... peripheral #blood #smear
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Immobilization - Crush injury ... - Electrical injury ... exhaustion, Heat injury ... Influenza, TSS, Herpes ... kidney tubular cells
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... Rapidly rising blast cells ... : Granulocytic cells ... • Peripheral smear ... Leukemia #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Skin: - CLL cells ... • Peripheral smear ... : Smudge cells or ... basket cells can ... diagnosis #workup #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... number of CD34+ cells ... number of CD34+ cells ... Number of CD34+ cells ... Aplastic #Anemia #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Peripheral smear ... lymphocytes, smudge cells ... Lymphocytic #Leukemia #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
caused by blood cells ... Peripheral Smear ... , and the cells ... Peripheral blood smear ... diagnosis #hematology #oncology
Grouped Pustules on an Erythematous Base - On physical examination, grouped, coalescing pustules that had scalloped
stain (Tzanck smear ... multinucleated giant cells ... Derm #Pathology #Herpes ... Pustules #Tzsanck #Smear ... #Microscopy #NEJM
Melanoma tumour progression (based on the Clark model) - Benign melanocytic nevi: controlled proliferation of normal
E-cadherin helps ... confine the cells ... intraepidermally but a few cells ... allow malignant cells ... Pathophysiology #Oncology
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