12 results
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
peripheral-blood smear ... revealed 25% plasma cells ... stain) #Clinical #HONC ... PlasmaCell #Leukemia #Smear ... #NEJM
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... anemia Sickled red cells ... disease Bite cells ... Alcohol abuse, Heavy metal ... Peripheral #Blood #Smear
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
🔬Tumor cells are ... 𝐩𝐫𝐨𝐥𝐲𝐦𝐩𝐡𝐨𝐜𝐲𝐭𝐞𝐬: small to medium ... size lymphoid cells ... Prolymphocytes #Smear
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
peripheral-blood smear ... acanthocytes (or spur cells ... Spur cells acquire ... #NEJM #clinical ... peripheral #blood #smear
Hemolysis in Hereditary Spherocytosis. Panel A shows the structure of a normal red cell and a
spleen in which red cells ... between endothelial cells ... Pathophysiology #Honc ... HereditarySpherocytosis #NEJM
Immunosuppressive Strategies for the Prevention or Treatment of Acute GVHD. Panel A shows several classic immunosuppressive
of activated T cells ... Pathophysiology #IM #Honc ... Immunosuppression #NEJM
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytes • Median ... • Peripheral smear ... lymphocytes, smudge cells
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
caused by blood cells ... Peripheral Smear ... Exposure to heavy metal ... , and the cells ... Peripheral blood smear
The Effect of Zinc on the Enteral Absorption of Copper. Panel A shows how copper (Cu)
) and divalent metal ... of intestinal cells ... CopperAbsorption #NEJM
Radiation-Induced Angiosarcoma after Breast-Cancer Treatment - Physical examination revealed an area of skin 10 cm in
cm in diameter, medial ... Clinical #Derm #Honc ... Radiation #Microscopy #NEJM