807 results
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Biliary Cirrhosis - Pathophysiology ... relative with PBC Pathophysiology ... the protective bicarbonate-rich ... Biliary #Cirrhosis #Pathophysiology
Nephron Remodeling as a Mechanism of Diuretic Resistance. When high doses of loop diuretics are used
and the chloride–bicarbonate ... #Pathophysiology
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Decreased serum bicarbonate ... level < 200 mg/dL Pathophysiology
Intercalated cells response to Metabolic Alkalosis and Metabolic Acidosis
 • Type B Intercalated Cell - "B"
Cell - "B" for Bicarbonate ... Intercalated #cells #pathophysiology
#Bicarbonate #algorithm #differential
#Bicarbonate #algorithm
ECG Changes in Hyperkalemia and Treatment
Membrane Stabilization
 - Calcium gluconate or chloride 
Redistribution
 - Insulin
Albuterol - Sodium bicarbonate
Approach to Elevated Bicarbonate (HCO3)
Risk Factors for Hypercapnea? (Hx of COPD, OSA, sedative use, CNS/muscular disorders?)
(+)
Approach to Elevated Bicarbonate ... UnremarkableLab #Bicarbonate
Causes of Metabolic Acidosis - Gap and Non-Gap - Differential Diagnosis Algorithm
 • Elevated Anion Gap
(<14) (Loss of Bicarbonate
Renal Tubular Acidosis (RTA) 
Type 1 - Failure of secretion
Type 2 - Bicarbonate wasting
Type 4 -
secretion Type 2 - Bicarbonate
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... #Diabetes #Pathophysiology