2745 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
of clinical and biological ... evidences, Biological ... confusion • Biological ... immunosuppressants or biologics ... Lymphohistiocytosis #diagnosis #management
Biologic therapy for eosinophilic asthma 
• Mepolizumab (Nucala) 
  • Anti-lL-5, 100 mg SQ q4
Biologic therapy ... eosinophilic #asthma #Biologic ... pharmacology #pulmonary #management
Overview of Biologics used for psoriasis

Information gathered from various phase 2 and phase 3 studies of
Overview of Biologics ... #clinical #management
Guidelines for Perioperative Management of Antirheumatic Medication in Patients with Rheumatic Diseases Undergoing Elective Total Hip
Perioperative Management ... • DMARDS • Biologics ... perioperative #guidelines #management
Proposed algorithm for choice of therapy or disease monitoring in sarcoidosis.
Anti-inflammatory therapy:
 • Prednisolone
 • Prednisolone
Third-line drugs (biologics ... Neurostimulants • Biologics ... sarcoidosis #algorithm #management
Eosinophilic Gastroenteritis: Treatment Options Based on Severity of the Disease
Mild:
 • Trial of PPI
 • Trial
Elemental diet • Biologic ... Gastroenteritis #Treatment #management
Refractory Eosinophilic Esophagitis (EOE) Management Algorithm
Initial treatment with topical steroids
Initial treatment with dietary elimination
Continued EoE nonresponse:
Esophagitis (EOE) Management ... Biologics? ... #Esophagitis #Management
JAK Inhibitors in 2019

Role in the therapeutic strategy in 2019
 • RA: 2nd line after failure
cDMARDs and/or biologics ... #Rheumatology #Management
Orofacial Granulomatosis - Diagnosis and Management Algorithm
Idiopathic OFG: isolated swelling of the lips, BX+ non-caseating granuloma
Melkersson-Rosenthal
Diagnosis and Management ... Immunomodulator • Biologic ... Granulomatosis #Diagnosis #Management
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
odynophagia + Biological ... Disease #diagnosis #management