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syndrome treatment cardiomyopathy endocarditis hematology hemophagocytic hlh lymphohistiocytosis macrophage mas peripartum sjogrens summary
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... : SLE+++, Adult-onset ... Still disease, ... #management #treatment ... #summary #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... erythematosus [SLE ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
• Autoimmune (SLE ... Cerebral > Splenic, pulmonary ... Differential Diagnosis ... Endocarditis Diagnosis ... #management #cardiology
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... Valvular heart disease ... cardiomyopathy • Pulmonary ... orthopnea, PND, LE ... #management #cardiology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... : • 10%-15% Pulmonary ... , INC risk PE, Pulmonary ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
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