11 results
Pathophysiology of Hemolytic Anemia
 - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects)
 -
Pathophysiology ... of Hemolytic Anemia ... in RBC internal contents ... #Hemolytic #Anemia ... #hematology
Aplastic Anemia Summary

 • Definition
 • Pathophysiology
 • DDx: AA vs Hypocellular MDS
 • Expectation
 •
Aplastic Anemia ... Definition • Pathophysiology ... Expectation • Rx Algorithm ... #Aplastic #Anemia ... diagnosis #oncology #hematololgy
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... Pathophysiology ... instability - New-onset ... #Diagnosis #Dermatology ... Color #Targetoid #Algorithm
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... disease states Pathophysiology ... characterized by sudden onset ... • Nocturnal onset ... Gout #Comparison #rheumatology
Chest Pain Diagnosis and Management Algorithm
STEMI:
 - Hx: Pressure like CP, Radiation to arm/jaw, CAD risk
and Management Algorithm ... - Hx: Sudden onset ... underlying dz (SLE, uremia ... , Dyspnea, H/O COPD ... Diagnosis #Management #Algorithm
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
nephrocalcinosis • CPPD ... • Pernicious anemia ... collection with EDTA Pathophysiology ... Hyophosphatasia #hepatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Deposition Disease (CPPD ... ) Pathophysiology ... calcium to form CPP ... characterized by sudden onset ... Deposition #Disease #Rheumatology
General Approach to Anemia - Differential Diagnosis Framework
1) Check reticulocyte count to determine if hypo/hyper-proliferative
2) Exclude
General Approach to Anemia ... MCV & clinical context ... uw_IMresidency #anemia ... differential #diagnosis #hematology ... #algorithm #reticulocyte
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
injury 2) Abrupt onset ... microangiopathic hemolytic anemia ... (MAHA) Pathophysiology ... Renal #Crisis #rheumatology
Management of Pruritus in Patients with Chronic Kidney Disease
Pruritus with no primary lesions - differential diagnosis:
pruritus • Hematologic ... Iron deficiency anemia ... sparingly BID-QID (onset ... Pruritus #Treatment #Algorithm ... Hemodialysis #Uremic #Uremia