11 results
diagnosis rheumatology blood disease hemophagocytic hlh lymphohistiocytosis product pseudogout reactions signs symptoms alkaline alp chondrocalcinosis comparison crisis deposition gout hemeonc
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... intracellular contents ... TLS #diagnosis #management ... #hematology
Pseudogout: pathogenesis and clinical findings - Idiopathic (vast majority of cases) -> Mechanism unknown - Familial
vast majority of cases ... > Clearance of calcium ... mineralization of calcium ... joint (sudden onset ... Signs #Symptoms #Pathophysiology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... precipitates with calcium ... characterized by sudden onset ... • Nocturnal onset ... Gout #Comparison #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pseudogout Summary - Calcium ... ) Pathophysiology ... characterized by sudden onset ... Deposition #Disease #Rheumatology ... #diagnosis #management
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
nephrocalcinosis • CPPD ... collection with EDTA Pathophysiology ... ALP -> PPi and Calcium ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... 4) Average age onset ... survival is 93-95% Pathophysiology ... fibrosis. 4) Calcium ... Sarcoidosis #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... SLE+++, Adult-onset ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... resembles ARDS, onset ... binds to serum calcium ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... resembles ARDS, onset ... binds to serum calcium ... Transfusions #diagnosis #management ... #hematology #reactions
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
injury 2) Abrupt onset ... anemia (MAHA) Pathophysiology ... of arteries Management ... • Refractory cases ... Renal #Crisis #rheumatology
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