24 results
Diagram of different types of bone tumors that can occur around the knee on XRay -
different types of bone ... ) • Enostosis/bone ... docskalski #Knee #Bone ... #Bony #Differential ... #Radiology #XRay
Diagram of different types of bone tumors that can occur around the knee on XRay
Age <
different types of bone ... Simple/unicameral bone ... • Aneurysmal bone ... #Differential # ... Diagnosis #Radiology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver, bone ... : Inhibitor of bone ... Malnutrition • Wilson's disease ... formation causing poor bone ... Skeletal: - Bone
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Epidemiology: young adults ... • Clinical features ... extranodal) - Tumor ... #differential # ... hematology
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
- MSK Radiology ... fragmentation and mild bone ... tibial tuberosity Differential ... marrow edema and bony ... #Radiology #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
arthritis (sJIA) • Adult-onset ... hemophagocytosis in the bone ... CD163 staining of bone ... is found in the bone ... Activation #Syndrome #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... , Biological + Bone ... /ml, ↑ LDH • Bone ... : SLE+++, Adult-onset ... Still disease,
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Diagnosis Framework ... - Giant cell tumor ... - Aneurysmal bone ... #diagnosis #msk
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... phenomenon CLL Diagnosis ... cells can indicate disease ... Warm AIHA • Bone ... workup #oncology #hematology
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... mutations - BMPR2 (bone ... multifactorial mechanisms Hematologic ... Classification #Diagnosis ... #Differential #