37 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... • XR, MRI to ... BrighamChiefs #Bone ... diagnosis #causes ... #hematology
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
Peripheral Vascular Disease ... fractured long bone ... • Dislocated Bone ... Vascular #JointPain #MSK ... #Orthopedics #Causes
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
stimulation (placenta/Bone ... - Highest • Bone ... Intestine - Other causes ... - Bone symptoms ... #hepatology
Coronary Artery Embolism - Etiology and Scoring
Etiology:
 • Direct: Clot (LV thrombus, LAA Thrombus), Valve (Vegetation,
- Most Common Cause ... source based on ... TTE, TEE, CT or MRI ... rheumatic valve disease ... #diagnosis #differential
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Diagnosis Algorithm ... Tumours - See Bone ... • Bone Marrow ... Fractures #Pathologic #MSK ... #Orthopedics #Causes
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
- MSK Radiology ... fragmentation and mild bone ... tibial tuberosity Differential ... marrow edema and bony ... #msk
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
g/dl LLN B - Bony ... more: • Clonal bone ... focal lesions on MRI ... Causes of false- ... Gammopathies #MGUS #diagnosis
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Diagnosis Framework ... Myeloproliferative disease ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... Drug induced - Bone ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
Bisphosphonate suppresses bone ... damage weakens the bone ... Femur #Fractures #msk ... #differential # ... causes #pathophysiology