4 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Rapidly Progressive Glomerulonephritis ... staining): • Low Complement ... Post-strep GN, Lupus ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... antigen, leading to complement ... Complement activation ... Post-streptococcal glomerulonephritis ... , and systemic lupus
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
table of types of hypersensitivity ... antigens, leading to complement ... they activate complement ... Post-streptococcal glomerulonephritis ... , Systemic lupus
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Skin ulcers - Glomerulonephritis ... • Low serum C4 complement ... vasculitis • Hypersensitivity ... (e.g. systemic lupus