9 results
diagnosis differential adaptive agammaglobulinemia allergy c5c9deficiency cascade causes dcs dendriticcells fever glomerulonephritis gonorrhea hematology humoral hypersensitivityreaction immunecompromised immunocompromised inflammation inflammatory
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Continued Innate Immunity ... dead tissue • Complement ... activation of complement ... #Inflammation #pathophysiology ... #immunology
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Humoral Immunity ... contribute to immunity ... exposure #Humoral #Immunity ... #pathophysiology ... #immunology
How dendritic cells (DCs) orchestrate adaptive immunity 1- Sensing of microbial and damage signals by DCs 2- Phenotypic
orchestrate adaptive immunity ... DCs #adaptive #immunity ... #immunology #pathophysiology
C5-C9 Deficiency - Pathogenesis and Clinical Findings Note: • Risk of invasive meningococcal disease is 1000-10000x higher
is rare Normal complement ... response: The complement ... activation -> Complement ... #pathophysiology ... #immunology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... staining): • Low Complement ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Gonorrhea: Pathophysiology - Neonatal Transmission -> Direct contact of patient mucosa with mother's infected mucosa while
Gonorrhea: Pathophysiology ... to avoid host immunity ... activation of complement ... #Gonorrhea #Pathophysiology
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
activates the complement ... HypersensitivityReaction #Allergy #Immunology ... #pathophysiology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
adaptive humoral immunity ... Agammaglobulinemia #XLinked #pathophysiology ... #immunology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Differential Diagnosis Algorithm ... Cell Mediated Immunity ... Periodontal Disease Complement ... Differential #Diagnosis #Algorithm
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