10 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low ... Complement: Post-strep ... #differential #diagnosis ... #algorithm #rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... , type 1 (50%-80% ... Hypocomplementemia #Low ... #Complement #CHAMPS ... #Mnemonic #diagnosis
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Complement activation ... Post-streptococcal glomerulonephritis ... #Classification ... Pathophysiology #Allergy #Diagnosis ... #Reactions #Table
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... Allergen-specific lgE causes ... Post-streptococcal glomerulonephritis ... #allergy #table ... #classification
Hypokalemia - Differential Diagnosis
Poor Intake 
 - Starvation
 - Anorexia
GI Losses 
 - Vomiting / NG
- Differential Diagnosis ... tubular acidosis (Types ... and 2, but not type ... #Low #Potassium ... #Table #Classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Skin ulcers - Glomerulonephritis ... Labs/Diagnosis: ... factor level • Low ... serum C4 complement ... #types #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... tract, and often causes ... against MPO • Complement ... (Low levels mixed ... #rheumatology #classification
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
in monitoring low-level ... or alternative complement ... cryoglobulinemias (types ... testing #workup #diagnosis ... #glomerulonephritis
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
ASA class If ... event, follow ACC algorithm ... Orthopedic • Low ... What is the type ... stratification #diagnosis
6/02/2022 UPDATE: This assay is designed to detect non-variola orthopoxviruses, including monkeypox virus. It is not
risk of smallpox –low ... /pdfs/smallpox-diagnostic-algorithm-poster ... specimens from low ... The type of specimen ... See table below