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hemolytic cold cvid immunodeficiency immunology lymphocytic mds myelodysplasia myelodysplastic systemic workup
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... , CLL, lymphoma, ... agglutin disease ... #Causes #differential ... #diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... Diagnosis: • hemolytic ... the RBCs causing intravascular ... #hemolytic #anemia ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
SLL CLL Epidemiology ... • Richter’s Syndrome ... • Sezary syndrome ... #Leukemia #diagnosis ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
' syndrome in the ... Shrinking lung syndrome ... Kidney disease common ... : • Chronic B-cell ... #Diagnosis #Rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Common Variable ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... #immunology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
MDS carries a variable ... Most common cytopenia ... Cell Leukemia ... #diagnosis #hematology ... #oncology
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