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oncology lymphocytic behcet cvid erythematosus extravascular gap globulin hemeonc hemolysis hemolytic hodgkins immunodeficiency immunology intravascular myelodysplasia myelodysplastic polychondritis protein proteingap
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
SLL CLL Epidemiology ... : • Most common ... • Neutropenia, anemia ... #Leukemia #diagnosis ... workup #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... (CLL) and/or Small ... lymphoma #Leukemia ... #Hematology #Oncology ... #Diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
usually IgG) (e.g. lupus ... , CLL, lymphoma, ... lymphoproliferative disorders ... #differential # ... diagnosis #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... • Disorder of ... lymphoma (Richter ... #hematology #hemeonc ... #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... autoimmune hemolytic anemia ... DDX - Other causes ... #immunology #hematology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Kidney disease common ... : • Chronic B-cell ... and leukemia • ... #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Most common cytopenia ... Marrow Failure • Chronic ... Cell Leukemia ... Myeloproliferative Disease ... #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
(HL) is an uncommon ... • Autoimmune disorders ... #diagnosis #classification ... #hematology #oncology ... #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
of age • Most common ... ) Differential Diagnosis ... , Lymphoma Ocular ... #diagnosis #management ... signs #symptoms #rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
gastric tumors • Hematology ... : Lymphoma, Leukemia ... anemia • Other ... Comment on type ... #diagnosis #hematology
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