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rheumatology hemolytic vasculitis agglutinin cold hemolysis high hodgkins hyperkalemia infectiousdiseases intravascular leukemia lymphoma mds mycobacteria myelodysplasia myelodysplastic nontuberculous ntm potassium
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... usually IgG) (e.g. lupus ... , CLL, lymphoma, ... #Causes #differential ... #diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... include fatigue ... anemia • Cold ... younger pts) Differential ... #hematology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Clinical evidence of (fatigue ... Classification: ... fibromyalgia) • Infections ... #Diagnosis #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... Symptoms: • Fatigue ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Symptoms: • Fatigue ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology ... #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... • Fevers • Fatigue ... vasculitis, and SLE ... #diagnosis #rheumatology ... #classification
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
: syßtemic lupus ... erythematosus ( ... SLE), sickle cell ... , sickle cell anemia ... #Diagnosis #High
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Hematologic malignancy ... Bone Marrow - Anemia ... 35 percent) • Fatigue ... #differential #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... : • Fevers • Fatigue ... ischemia • Skin: Erythematous ... tract, and often causes ... #Diagnosis #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Immunohistochemical studies (to differentiate ... number of sites of disease ... #hematology #oncology ... #management
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