Bursitis diagnosis sle pulmonary classification copd management disease hematology syndrome hepatology hemolytic agglutinin autoimmune hypogammaglobulinemia

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Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
1. Cold Agglutinins (CAD)
2. Donath-Landsteiner

Agglutinin Disease ... Agglutinin Syndrome ... Diagnosis: • hemolytic ... #agglutinin #disease ... #hematology #diagnosis

Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
• Mechanical Trauma (Microangiopathic hemolytic anemia):

Diagnostic Framework ... ) - HELLP syndrome ... uremic syndrome ... agglutin disease ... #hematology #anemia

Hemolytic Anemia - Differential Diagnosis Algorithm
• Sickle cells - Consider sickle cell disease (diverse genotypes):

- Differential Diagnosis ... ): SS, SC, SE, Sβ ... agglutinins disease ... elliptocytosis, autoimmune ... Algorithm #workup #hematology

Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell

hemolytic anemia ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... #immunology #hematology ... #diagnosis #management

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