6 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Syndrome (MAS) ... [SLE], AOSD) • ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... • Anti-Ro/SSA autoantibodies ... , dermatomyositis ... Kidney disease common ... #Diagnosis #Rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
years Clinical ... lung disease (GLILD ... Chest CT: • Ground-glass ... hemolytic anemia) • Systemic ... hypogammaglobulinemia #immunology #hematology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
papules Clinical ... : • ILD was diagnosed ... #AntiNXP2 #Dermatomyositis ... #rheumatology # ... dermatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Inflammatory Myopathies: Commonly ... lung disease Malignancy ... lung disease • ... lung disease • ... Myositis #Myopathy #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
as SLE, atherosclerotic ... purpura: Strong sign ... Nodosa: • PAN most commonly ... ischemia • Skin: Erythematous ... #Rheumatology