8 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... vasculitis #Dermatologic ... GPA #dermatology ... #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Diagnosis: • ANCA-associated ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... #Diagnosis #Rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Liver diseases and ... lung disease (GLILD ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
• Microscopic Polyangiitis ... often causes arthritis ... to exclude are infections ... SLE) • Urinalysis ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
, such as SLE, atherosclerotic ... ischemia • Skin: Erythematous ... often causes arthritis ... inflammatory lesions - interstitial ... #Diagnosis #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... Nephrogenic DI Hematologic ... MALT Lymphoma • Lung ... #Rheumatology #
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Hematologic malignancy ... Disease: Clinical ... #differential # ... diagnosis #infectiousdiseases