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differential management vasculitis activation antibodies antinuclear antinxp2 common cryoglobulinemia cryoglobulins cvid dermatomyositis hodgkins hypogammaglobulinemia immunodeficiency immunology infectiousdiseases lymphoma macrophage mycobacteria
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... Classification: ... fibromyalgia) • Infections ... #Diagnosis #Rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
years Clinical ... lung disease (GLILD ... Chest CT: • Ground-glass ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
rash) • Heart, lung ... SLE], AOSD) • Infection ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... MAC pulmonary disease ... Hematologic malignancy ... Disease: Clinical ... Imaging, high res CT
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... lupus erythematosus ... LFT • ESR • ANA ... #rheumatology # ... classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... • Autoimmune diseases ... (e.g. systemic lupus ... erythematosus ( ... #rheumatology #
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
papules Clinical ... cause weakness ... had more severe disease ... #rheumatology # ... dermatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... ischemia • Skin: Erythematous ... often causes arthritis ... inflammatory lesions - interstitial ... #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Hodgkin Lymphoma - Clinical ... ) Classification ... number of sites of disease ... #hematology #oncology
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