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management differential blood classification product reactions vasculitis cvid dermatologic granulomatosis hiv hodgkins hypogammaglobulinemia immunodeficiency immunology infectiousdiseases lupus lymphoma macrophage oncology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
) is common and ... can appear as an ... GPA causes disease ... #dermatology #rash ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
fibromyalgia) • Infections ... Arthritis: • Joint pain ... Kidney disease common ... Chronic B-cell activation ... #Diagnosis #Rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
years Clinical ... lung disease (GLILD ... Chest CT: • Ground-glass ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... inflammatory lesions-interstitial ... to exclude are infections ... SLE) • Urinalysis ... #rheumatology #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
rash) • Heart, lung ... [SLE], AOSD) • ... Infection (eg, ... #Management #Hematology ... #Rheumatology
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... • CT: Halo sign ... papules, pustules, erythematous ... fever, rales, interstitial ... #AIDS #pulmonary
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... most commonly affects ... MPO > PR3 60/ GPA ... often causes arthritis ... #Rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
: Fever, flank pain ... Related Acute Lung ... Infection - Infection ... #Transfusion #diagnosis ... #management #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Hodgkin Lymphoma - Clinical ... hemolytic anemia • Pain ... number of sites of disease ... classification #hematology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Sudden onset of pain ... as: • SLE • RA ... • Lymphoma • GPA ... /EGPA • RA Diagnosis ... Polychondritis #rheumatology
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