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differential classification management cryoglobulins phenotypes syndrome treatment types workup
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Diseases: • Homogeneous ... tissue disease ... (SLE), Sjogren's ... #Antibodies #ANA ... #patterns #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... (SLE), Sjogren's ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #patterns #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... vasculitis, rheumatoid ... • Mesenteric vasculitis ... inflammation Cutaneous Vasculitis ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
disease, and ocular ... : Systemic rheumatic ... as systemic lupus ... ) pattern: antibodies ... #rheumatology #
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... lupus erythematosus ... (SLE), rheumatoid ... arthritis, Sjögren's ... classification #rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... (antinuclear antibodies ... No necrosis, No vasculitis ... #Related #Disease ... workup #treatment #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
multisystemic disease ... demyelinating disease ... ) • Cutaneous vasculitis ... Vasculitis: • ... #Syndrome #Rheumatology
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