6 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... • Anti-Ro/SSA autoantibodies ... , dermatomyositis ... #Diagnosis #Rheumatology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... Clinical history ... concentration PET-CT ... (antinuclear antibodies ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
> 95% (IgG anti-chromatin ... of autoantibodies ... Erythematosus ( ... #table #rheumatology ... #diagnosis #management
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
without these autoantibodies ... papules Clinical ... had more severe disease ... #AntiNXP2 #Dermatomyositis ... #rheumatology #
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... salivary ducts Clinical ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology