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differential antinuclear classification lupus macrophage mas patterns sjogrens systemic vasculitides
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... Polymyositis/Dermatomyositis ... , Interstitial Pulmonary ... #rheumatology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, dermatomyositis ... fibromyalgia) • Infections ... Induced Lupus: • Symptoms ... Chronic B-cell activation ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
to exclude are infections ... Presentation - Systemic Symptoms ... ) pattern: antibodies ... , and SLE) • Urinalysis ... #rheumatology #
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... MALT Lymphoma • Lung ... #Rheumatology # ... Diagnosis #Management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
[SLE], AOSD) • ... Infection (eg, ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... ischemia • Skin: Erythematous ... • Progressive symptoms ... inflammatory lesions - interstitial ... #Rheumatology
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