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differential infectiousdiseases management vasculitis antinuclear autoimmune classification common cvid hiv hypogammaglobulinemia immunodeficiency lupus mycoses myopathy myositis patterns systemic variable vasculitides
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... Polymyositis/Dermatomyositis ... , Interstitial Pulmonary ... #rheumatology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, dermatomyositis ... fibromyalgia) • Infections ... Induced Lupus: • Symptoms ... with Lupus: • Chronic ... #Diagnosis #Rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... lung disease ... lung disease (GLILD ... Chest CT: • Ground-glass ... #hematology #diagnosis
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tenderness → Consider infectious ... lung disease Malignancy ... lung disease • ... lung disease • ... Myositis #Myopathy #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... purpura: strong sign ... ) pattern: antibodies ... SLE) • Urinalysis ... #rheumatology #
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... Pseudomonas FUNGAL ... • CT: Halo sign ... Constitutional symptoms ... #AIDS #pulmonary
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... purpura: Strong sign ... ischemia • Skin: Erythematous ... Eosinophilia, asthma, chronic ... #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms ... • Rheumatologic ... stain of clinical ... yeast • At risk: AIDS ... or chronic pulmonary
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