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differential antinuclear antinxp2dm classification dermatology igg4 lupus patterns phenotypes related sjogrens syndrome systemic treatment workup
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
vasculitis, rheumatoid ... , dermatomyositis ... • Mesenteric vasculitis ... inflammation Cutaneous Vasculitis ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis and Vasculitides ... Presentation - Systemic Symptoms ... ) pattern: antibodies ... , and SLE) • Urinalysis ... #rheumatology #
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... , Polymyositis/Dermatomyositis ... , Interstitial Pulmonary ... #rheumatology #diagnosis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... ischemia • Skin: Erythematous ... • Progressive symptoms ... inflammatory lesions - interstitial ... #Rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
• Antibodies targeting ... papules Clinical ... #AntiNXP2 #Dermatomyositis ... #diagnosis #management ... #rheumatology #
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
Clinical history ... concentration PET-CT ... No necrosis, No vasculitis ... #diagnosis #management ... workup #treatment #rheumatology
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