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management chronic cll leukemia lymphocytic cvid differential erythematosus hemeonc hodgkins hypogammaglobulinemia immunodeficiency immunology lupus polychondritis relapsing sjogrens syndrome systemic variable
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Granulomatous lymphocytic interstitial ... lung disease (GLILD ... Chest CT: • Ground-glass ... hypogammaglobulinemia #immunology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
(HL) is an uncommon ... History of EBV infection ... (NSHL) - (most common ... #diagnosis #classification ... #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... Complications: 1) Infection ... to large cell lymphoma ... chemotherapy for low-risk disease ... #hematology #hemeonc
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... fibromyalgia) • Infections ... Induced Lupus: • Symptoms ... Kidney disease common ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... • Lung Adenocarcinoma ... Treatment: ... Sjogrens #Syndrome #Rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
: • Most common ... with no early symptoms ... weeks without infection ... #workup #oncology ... #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
to exclude are infections ... LFT • ESR • ANA ... SLE) • Urinalysis ... #rheumatology # ... classification
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... cases such as: • SLE ... • Lymphoma • ... affected tissue Treatment ... Polychondritis #rheumatology
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