9 results
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... lung disease ... lung disease (GLILD ... #immunology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... Complications: 1) Infection ... to large cell lymphoma ... Leukemia #oncology #hematology ... #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... • Lung Adenocarcinoma ... Treatment: ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
: • Most common ... Orange or Hep C Clinical ... with no early symptoms ... weeks without infection ... workup #oncology #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... fibromyalgia) • Infections ... common • Antihistone ... with Lupus: • Chronic ... #Rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... (NSHL) - (most common ... #diagnosis #classification ... #hematology #oncology ... #management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Eosinophilia, asthma, chronic ... to exclude are infections ... vasculitis, and SLE ... #rheumatology # ... classification
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
droppings • Most common ... pulmonary symptoms ... • Rheumatologic ... pulmonary infection ... #Management #Infections
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
cases such as: • SLE ... • Lymphoma • ... affected tissue Treatment ... Polychondritis #rheumatology ... #diagnosis #management